Table 1.

Antibiotics commonly used in the treatment of mastitis. Please note that amoxicillin without clavulanate is not a suitable treatment option due to high degree of resistance.

Antibiotic	Dosage	Notes
Cephalexin	500 mg × 4 times/day	Not suitable in case of allergy to penicillin with sensitivity to cephalosporins or with anaphylactic reaction to penicillin (severe allergy).
Amoxicillin-clavulanate	875 mg × 2 times/day
Dicloxacillin	500 mg × 4 times/day
Clindamycin	300 mg × 4 times/day	May be effective in the case of methicillin-resistant Staphylococcus aureus. An appropriate option in case of severe allergy to penicillin.
Trimethoprim-sulfamethoxazole	800–160 mg × 2 times/day	May be effective in case of methicillin-resistant Staphylococcus aureus. Avoid using if the baby is less than one months old, or if the baby is jaundiced, ill, premature or G6PD