Skip to main content
. 2020 Jul 28;12(8):2092. doi: 10.3390/cancers12082092

Figure 1.

Figure 1

Inhibitory activities towards AKR1C3 of three compounds designated MF-11, MF-14 and MF-15. (A) Three compounds with a chalcone and dihydrochalcone scaffold were tested upon their capacity to inhibit AKR1C3 at a concentration of 10 µM using an enzyme inhibition assay as described under material and methods. Data are represented as mean percentage inhibition plus SEM of three independent experiments compared to the mock control (DMSO). A positive control (CAS 745028-76-6) was used at a concentration of 1 µM. (B) Chemical structures of MF-11, MF-14, and MF-15 with 2′-(2-hydroxy)-benzyl moiety are marked in red.