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. 2020 Aug 18;12(8):2332. doi: 10.3390/cancers12082332

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The methylation levels of SCAND3 and Myo1g in seven hepatocellular carcinoma (HCC) cell lines and the normal hepatocyte cell line LO2. (A) SCAND3 average methylation levels in seven HCC cell lines (HepG2, HepB3, MHCC97H, MHCC97L, SK-Hep-1, Huh7, PLC) and LO2 were 92.07%, 90.53%, 89.23%, 93.64%, 91.60%, 61.73%, 94.07%, 8.07%, respectively. (B) Myo1g average methylation levels in seven HCC cell lines (HepG2, HepB3, MHCC97H, MHCC97L, SK-Hep-1, Huh7, PLC) and LO2 were 29.73%, 87.00%, 94.10%, 65.17%, 96.96%, 89.30%, 87.37%, 14.47%, respectively. SCAND3 and Myo1g hypermethylation were more prominent in seven HCC cell lines than in LO2. Statistical comparisons were computed using the unpaired t-test, * p < 0.05.