Table 3.
Diagnostic values of SCAND3 and Myo1g methylation levels in AFP-negative HCC patients.
| Markers | Se (%) | Sp (%) | PPV (%) | NPV (%) | Accuracy (%) | AUC (95% CI) | Kappa |
|---|---|---|---|---|---|---|---|
| SCAND3 | 66 | 94.7 | 80.5 | 89.4 | 87.5 | 0.804 (0.720–0.887) | 0.646 |
| Myo1g | 74 | 84.8 | 61.7 | 90.8 | 82.1 | 0.794 (0.715–0.872) | 0.551 |
| SCAND3 + Myo1g | 92 | 79.5 | 59.7 | 96.8 | 82.6 | 0.857 (0.799–0.916) | 0.605 |
Se, sensitivity; Sp, specificity; PPV, positive predictive value; NPV, negative predictive value; AUC, area under the curve; CI, confidence interval; AFP, alpha-fetoprotein.