Table 2.
Characteristics | Non-Long Survivors n = 284 |
Long-Term Survivors n = 120 |
Total n = 404 |
p-Value | |||
---|---|---|---|---|---|---|---|
N | % | N | % | N | % | ||
Surgery type | <0.001 | ||||||
Primary | 133 | 46.8 | 81 | 67.5 | 214 | 53.0 | |
Interval surgery | 151 | 53.2 | 39 | 32.5 | 190 | 47.0 | |
Digestive resection | <0.001 | ||||||
0 | 87 | 43.1 | 66 | 60.0 | 153 | 49.0 | |
>1 | 115 | 56.9 | 44 | 40.0 | 159 | 51.0 | |
Missing | 82 | 10 | 92 | ||||
Splenectomy | 0.241 | ||||||
No | 128 | 96.2 | 75 | 92.6 | 203 | 94.9 | |
Yes | 5 | 3.8 | 6 | 7.4 | 11 | 5.1 | |
Missing | 151 | 39 | 190 | ||||
Primary or interval surgery | 0.192 | ||||||
Complete (Gross total resection) | 160 | 56.3 | 76 | 63.3 | 236 | 58.4 | |
Incomplete (Macroscopic residual disease) | 124 | 43.7 | 44 | 36.7 | 168 | 41.6 | |
Initial PCI | |||||||
Median (range) | 14 (0–33) | 11 (0–24) | 13 (0–33) | <0.001 | |||
<17 | 165 | 63.0 | 87 | 82.1 | 252 | 68.5 | <0.001 |
≥17 | 97 | 37.0 | 19 | 17.9 | 116 | 31.5 | |
Missing | 22 | 14 | 36 | ||||
Chemotherapy | |||||||
Neoadjuvant CT | 147 | 51.9 | 37 | 31.1 | 184 | 45.8 | <0.001 |
Missing | 1 | 1 | 2 | ||||
1st CT line regimen | 0.793 | ||||||
Platinum salts/Paclitaxel | 223 | 79.7 | 97 | 82.2 | 320 | 80.4 | |
Platinum salts/Exoxan | 30 | 10.7 | 12 | 10.2 | 42 | 10.6 | |
Others | 27 | 9.6 | 9 | 7.6 | 36 | 9.0 | |
Missing | 4 | 2 | 6 | ||||
Number of cycles | 0.946 | ||||||
Median (range) | 6 (1–14) | 6 (3–12) | 6 (1–14) | ||||
Missing | 6 | 1 | 7 | ||||
Sensibility to 1st CT line | 0.001 | ||||||
Refractory/Resistant | 85 | 31.8 | 6 | 5.0 | 91 | 23.5 | |
Sensible | 181 | 68.2 | 114 | 95.0 | 295 | 76.5 | |
Missing | 18 | 0 | 18 | ||||
Treatment-free Interval (months) | <0.001 | ||||||
Median (range) | 8.5 (0.4–47.2) | 23.9 (0.7–121.6) | 11 (0.4–121.6) | ||||
<18 | 149 | 85.6 | 35 | 42.2 | 184 | 71.6 | |
≥18 | 25 | 14.4 | 48 | 57.8 | 73 | 28.4 | |
Missing/No 2nd CT line | 110 | 37 | 147 | ||||
Progression-free Interval (months) | <0.001 | ||||||
Median (range) | 14.5 (0.4–56.6) | 43.4 (2.3–248.2) | 17.4 (0.4–248.2) | ||||
<18 | 187 | 66.6 | 17 | 14.2 | 204 | 50.9 | |
≥18 | 94 | 33.5 | 103 | 85.8 | 197 | 49.1 | |
Missing | 3 | 0 | 3 |
PCI: peritoneal carcinomatosis index. CT: chemotherapy.