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. 2020 Aug 5;12(8):2184. doi: 10.3390/cancers12082184

Table 2.

Treatments.

Characteristics Non-Long Survivors
n = 284
Long-Term Survivors
n = 120
Total
n = 404
p-Value
N % N % N %
Surgery type <0.001
Primary 133 46.8 81 67.5 214 53.0
Interval surgery 151 53.2 39 32.5 190 47.0
Digestive resection <0.001
0 87 43.1 66 60.0 153 49.0
>1 115 56.9 44 40.0 159 51.0
Missing 82 10 92
Splenectomy 0.241
No 128 96.2 75 92.6 203 94.9
Yes 5 3.8 6 7.4 11 5.1
Missing 151 39 190
Primary or interval surgery 0.192
Complete (Gross total resection) 160 56.3 76 63.3 236 58.4
Incomplete (Macroscopic residual disease) 124 43.7 44 36.7 168 41.6
Initial PCI
Median (range) 14 (0–33) 11 (0–24) 13 (0–33) <0.001
<17 165 63.0 87 82.1 252 68.5 <0.001
≥17 97 37.0 19 17.9 116 31.5
Missing 22 14 36
Chemotherapy
Neoadjuvant CT 147 51.9 37 31.1 184 45.8 <0.001
Missing 1 1 2
1st CT line regimen 0.793
Platinum salts/Paclitaxel 223 79.7 97 82.2 320 80.4
Platinum salts/Exoxan 30 10.7 12 10.2 42 10.6
Others 27 9.6 9 7.6 36 9.0
Missing 4 2 6
Number of cycles 0.946
Median (range) 6 (1–14) 6 (3–12) 6 (1–14)
Missing 6 1 7
Sensibility to 1st CT line 0.001
Refractory/Resistant 85 31.8 6 5.0 91 23.5
Sensible 181 68.2 114 95.0 295 76.5
Missing 18 0 18
Treatment-free Interval (months) <0.001
Median (range) 8.5 (0.4–47.2) 23.9 (0.7–121.6) 11 (0.4–121.6)
<18 149 85.6 35 42.2 184 71.6
≥18 25 14.4 48 57.8 73 28.4
Missing/No 2nd CT line 110 37 147
Progression-free Interval (months) <0.001
Median (range) 14.5 (0.4–56.6) 43.4 (2.3–248.2) 17.4 (0.4–248.2)
<18 187 66.6 17 14.2 204 50.9
≥18 94 33.5 103 85.8 197 49.1
Missing 3 0 3

PCI: peritoneal carcinomatosis index. CT: chemotherapy.