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. 2020 Aug 18;25(16):3756. doi: 10.3390/molecules25163756

Table 3.

LogD values of human serum stable radioconjugates determined in n-octanol/PBS buffer system.

Radioconjugate logD
68Ga- 177Lu-
APT-Et-DOTA, 5A 0.141 ± 0.019 0.708 ± 0.021
APT-Pr-DOTA, 5B 0.058 ± 0.016 0.654 ± 0.022
APT-Bu-DOTA, 5C 0.290 ± 0.018 0.777 ± 0.021
APT-Ac-HN-NH-DOTA, 5D −1.012 ± 0.017 −0.401 ± 0.015
APT-Ac-Et-DOTA, 5E −0.231 ± 0.015 0.500 ± 0.017