Table 4.

Docking scores and energy involvement of reference LasR inhibitors and screened hit molecules against LasR-LBD.

Ligands	Glide Gscore (kcal/mol)	Glide Energy (kcal/mol)	MMGBSA dg Bind (kcal/mol)
Results of reference LasR inhibitors
8	−10.24	−53.28	−75.43
10	−10.17	−55.49	−80.50
6	−10.10	−52.53	−75.53
13	−10.06	−56.90	−79.33
14	−10.01	−56.38	−79.76
4	−9.95	−52.45	−74.45
17	−9.28	−56.20	−76.42
Results of LasR inhibitors
Articaine	−9.01	−41.63	−46.27
Sulfamerazine	−9.68	−47.48	−52.74
Sulfametopyrazine	−8.37	−48.73	−52.71
Sulfapyridine	−8.07	−45.25	−51.35
Sulfadiazine	−8.27	−45.08	−44.23
Sulfamethazine	−7.86	−50.23	−51.16