Table 5.
Interaction analysis of reference LasR inhibitors against LasR-LBD.
| S. No. | Compound | Number of H Bonds | Interacting Atoms of Protein-Ligand Complex | Distance (Å) |
|---|---|---|---|---|
| 1 | 8 | 4 | TYR 56…Lig(O) | 1.81 |
| Lig(NH)…ASP 73 | 1.82 | |||
| TRP 60…Lig(O) | 2.11 | |||
| SER 129…Lig(O) | 2.13 | |||
| 2 | 10 | 4 | TRP 60…Lig(O) | 2.07 |
| TYR 56…Lig(O) | 1.97 | |||
| SER 129… Lig(O) | 2.08 | |||
| Lig(NH)…ASP 73 | 1.73 | |||
| 3 | 6 | 4 | TRP 60…Lig(O) | 2.21 |
| TYR 56…Lig(O) | 1.88 | |||
| SER 129…Lig(O) | 2.15 | |||
| Lig(NH)…ASP 73 | 1.79 | |||
| 4 | 13 | 4 | TYR 56…Lig(O) | 1.86 |
| SER 129…Lig(O) | 2.12 | |||
| Lig(NH)…ASP 73 | 1.83 | |||
| TRP 60…Lig(O) | 2.10 | |||
| 5 | 14 | 4 | TYR 56…Lig(O) | 1.97 |
| SER 129…Lig(O) | 2.08 | |||
| Lig(NH)…ASP 73 | 1.74 | |||
| TRP 60…Lig(O) | 2.08 | |||
| 6 | 4 | 4 | SER 129…Lig(O) | 2.13 |
| TYR 56…Lig(O) | 1.85 | |||
| Lig(NH)…ASP 73 | 1.82 | |||
| TRP 60…Lig(O) | 2.14 | |||
| 7 | 17 | 4 | TRP 60…Lig(O) | 2.18 |
| Lig(NH)…ASP 73 | 1.86 | |||
| SER 129…Lig(O) | 2.15 | |||
| TYR 56…Lig(O) | 1.89 |