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. 2020 Aug 12;25(16):3675. doi: 10.3390/molecules25163675

Figure 1.

Figure 1

HSA samples (20 µM) were incubated with 50 mM D-glucose in absence and presence of inhibitors garlic extract and epigallocatechin-3-gallate (EGCG) for 10 weeks. Inhibitory effect of garlic extract (1–100 mg/mL) (A) and EGCG (1–100 µM) (B) on the formation of advanced glycation end products (AGEs) were assayed. Results are presented as mean ± SD (n = 3). At each time interval, statistical significances were calculated against glycated samples without inhibitors. t test was adopted for the comparison between the two groups and significance is defined as ** p  <   0.01, *** p  <  0.001. Garlic extract at 10 and 100 mg/mL showed p < 0.001 when compared with 0 mg/mL. EGCG at 10 and 100 µM showed p < 0.001 and p < 0.01 respectively, when compared with 0 µM EGCG.