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. 2020 Aug 15;12(8):2300. doi: 10.3390/cancers12082300

Figure 4.

Figure 4

Functional significance of exosomes-mediated transfer of ITGA2 into PCa cells. (A) C4-2B, CWR-1Rca and E006AA cells were incubated with 10 µg/mL exosomes derived from PC-3 or DU145- for 3 days then cell proliferation assay was performed. Representative transwell migration and invasion assays are presented for C4-2B, CWR-1Rca and E006AA cells treated with or without 20 µg/mL exoPC-3 for 24 h. (B) Wound-healing assay was performed on C4-2B and E006AA cells incubated with or without exosomes derived from DU145 cells up to 72 h in 6-well plates. Each treatment was conducted in triplicate and at least 6 fields were captured under inverted bright microscope. * depicts significance at p < 0.05. Each experiment was performed in triplicate and independently repeated thrice.