Table 1.

Stevens-Johnson syndrome and toxic epidermal necrolysis induced by EGFR-tyrosine kinase inhibitors (EGFR-TKIs): characteristics of the current case and previously reported cases.

Author, Reported Year	Age	Sex	Nationality	EGFR-TKI	SJS/TEN	Onset	Treatment and Outcome
Huang, et al., 2015. [9]	42	female	Chinese	gefitinib	TEN	8 days	mPSL and IVIG, recovery after 40 days
Doesch, et al., 2016. [10]	79	female	German	afatinib	SJS	64 days	PSL, recovery after 60 days
Otsuka, et al., 2016. [11]	65	female	Japanese	afatinib	SJS	32 days	mPSL and IVIG, recovery after 60 days
Wang et al., 2018. [8]	51	male	Chinese	osimertinib	TEN	21 days	mPSL and IVIG, recovery after 30 days
Lin et al., 2019. [7]	57	female	Taiwanese	osimertinib	SJS	22 days	PSL, recovery after 60 days
Current case. 2020.	80	female	Japanese	osimertinib	TEN	32 days	PSL and IVIG, recovery after 80 days

Abbreviations: EGFR-TKI, Epidermal growth factor receptor tyrosine kinase inhibitor; IVIG, intravenous immunoglobulin; PSL, prednisolone; mPSL, methylprednisolone; SJS, Stevens-Johnson syndrome; TEN, toxic epidermal necrolysis.