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. 2020 Aug 19;10:1119. doi: 10.3389/fonc.2020.01119

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Copyright © 2020 Wang, Wu, Tu, Tao, Hu, Li, Zhu and Huang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The prognostic value of the risk score signature both in CGGA and TCGA datasets. (A) The patients with high-risk scores were correlated with a higher death rate and shorter survival time in gliomas. (B) Kaplan-Meier overall survival curves for patient data in the CGGA dataset. (C) The area under the curve (AUC) of ROC curves were 0.819, 0.793, and 0.746 in predicting 5-, 3-, and 1-year OS events from the CGGA dataset, respectively. (D–F) Validation of the risk score signature in the TCGA dataset using the same analysis. (G–J) Kaplan-Meier overall survival curves for patients in the CGGA dataset stratified by WHO grade and IDH-mutant status.