Table 1.
NAP with positive FTD (n = 20) | NAP without positive FTD (n = 20) | HC (n = 20) | Statistics | p-value | |
---|---|---|---|---|---|
Age (years) | 45.7 (11.91) † | 41.9 (10.87) | 43.9 (13.29) | F a = .5 | .61 |
Sex (male) | n = 15 | n = 7 | n = 11 | χ² b = 6.47 | .04 |
Verbal IQ | 103.6 (14.86) | 106.1 (12.61) | 103.25 (7.62) | Welch’s F c = .37 | .69 |
Inpatients | n = 7 | n = 0 | χ² d = 8.49 | .004 | |
F20.0 | n = 16 | n = 17 | χ² = .17 | .68 | |
F25.0 | n = 4 | n = 3 | χ² = .17 | .68 | |
Antipsychotic medication | n = 18 | n = 20 | χ² = 2.11 | .15 | |
CGI | 5.2 (1.36) | 3.65 (1.31) | t e = −3.67 | .001 | |
Duration of illness (years) | 17.25 (12.03) | 14.35 (9.91) | t = -.83 | .41 | |
SAPS | |||||
positive FTD | 2.8 (.7) | .35 (.59) | t = −12.03 | <.001 | |
Incoherence | 1.4 (1.55) | .05 (.22) | t = −4.25 | <.001 | |
Tangentiality | 2.6 (.82) | .05 (.22) | t = −13.41 | <.001 | |
Derailment | 2.25 (1.29) | .15 (.67) | t = −6.45 | <.001 | |
Illogicality | 1.5 (1.54) | .05 (.22) | t = −4.17 | <.001 | |
Circumstantiality | 1.7 (1.66) | .55 (.89) | t = −2.74 | .009 | |
Pressured speech | 2.15 (1.6) | .4 (.88) | t = −4.29 | <.001 | |
Distractibility | 1.25 (1.29) | .1 (.45) | t = −3.76 | .001 | |
Clanging | .6 (1.0) | 0 | t = −2.7 | .01 | |
Hallucinations | 1.6 (1.67) | 1.0 (1.49) | t = −1.2 | .24 | |
Delusions | 2.6 (1.23) | .7 (1.03) | t = −5.29 | <.001 | |
Bizarre Behavior | 1.3 (1.26) | .05 (.22) | t = −4.37 | <.001 | |
Inappropriate Affect | .85 (1.23) | .05 (.22) | t = −2.87 | .009 | |
SANS | – | ||||
Flat Affect | 1.55 (1.54) | 1.3 (1.13) | t = -.59 | .56 | |
Alogia | 1.0 (1.38) | .85 (1.09) | t = -.38 | .7 | |
Avolition/apathy | 1.95 (1.47) | 1.55 (1.47) | t = -.86 | .39 | |
Anhedonia/asociality | 2.6 (1.31) | 1.95 (1.47) | t = −1.48 | .15 | |
Attention | .95 (1.13) | .15 (.67) | t = −2.66 | .012 |
†Mean (SD); group comparisons between healthy controls (HC) and patients with non-affective psychoses (NAP) with and without formal thought disorder (FTD): aANOVA; bχ²-test; cWelch’s ANOVA; group comparisons between patients with and without FTD: dχ²-test; et-test for independent samples. CGI: Clinical Global Impression; SANS, Scale for the Assessment of Negative Symptoms; SAPS, Scale for the Assessment of Positive Symptoms.