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. 2020 Aug 19;11:1793. doi: 10.3389/fimmu.2020.01793

Figure 6.

Figure 6

LAIR-1 in vivo dynamics during inflammation. LAIR-1 gene expression was determined by array profiling and retrieved from publicly available datasets. (A) Lair1 expression in mouse skin samples recovered from injury up to 10 days following wounding inflicted via punch biopsy (GSE23006). Results are represented as mean with SD. Differences were considered statistically significant when *p < 0.05 vs. control sample (one-way ANOVA test). (B) Correlation between Lair1 expression and Ptprc (CD45), Adgre1 (F4/80), and Cd68 expression in mouse skin samples recovered from injury up to 10 days following wounding inflicted via punch biopsy (GSE23006). Correlations were assessed by the Pearson's correlation coefficient test. (C) LAIR-1 expression on peripheral blood monocytes from gram-negative sepsis patients during sepsis and following their recovery (GSE46955). Results are represented as mean with SD. Differences were considered statistically significant when *p < 0.05 (HC vs. sepsis basal and HC vs. sepsis recovery Unpaired t-test, sepsis basal vs. sepsis recovery Paired t-test).