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. 2020 Aug 9;10(8):1566. doi: 10.3390/nano10081566

Table 5.

The antiviral properties of AgNPs.

Virus Family Silver Nanoparticles Composition Mechanism of Action References
Herpes simplex virus type 2 (HSV-2) Herpesviridae Tannic acid-modified silver nanoparticles (13 nm) Interact with viral glycoproteins thus interfere with cell attachment [84]
Bacteriophage MS2 Leviviridae Magnetic hybrid colloid silver nanoparticles (15 nm) Damage proteins of the viral coat [85]
Murine novovirus Caliciviridae
Herpes simplex virus type 1 and type 2 (HSV-1 & HSV-2) Herpesviridae Mycosynthsized silver nanoparticles (4–31 nm) Block interaction of virus and cells [86]
Human parainfluenza virus type 3 (hPIV3) Paramyxoviridae
Human immunodeficiency virus (HIV) Retroviridae PVP-coated silver nanoparticles (30–50 nm) Inhibit the interaction between gp120 and cell membrane receptors [87]
H1N1 influenza A Orthomyxoviridae Chitosan-coated silver nanoparticles (3.5, 6.5, and 12.9 nm) Inhibit the viral contact with host cells and interaction of silver nanoparticles with viral glycoproteins [88]
Poliovirus Pure silver nanoparticles (7.1 nm) Bind with the viral particles thus prevent binding with host receptor and inhibition of viral proteins [89]
Respiratory syncytial virus (RSV) Paramyxoviridae PVP-coated silver nanoparticles (10 nm) Interfere with virus attachment by binding with gp120 glycoprotein [90]
Hepatitis B virus (HBV) Hepadnaviridae Silver nanoparticles (10 and 50 nm) Reduce the formation of HBV DNA by binding with the HBV dsDNA and virions [91]
Adenovirus type 3 (Ad3) Adenoviridae Silver nanoparticles (11.4 nm) Damaging the viral particles and bind to the viral DNA [92]