Table 1.

Main baseline characteristics of the 496 DCIS patients included in the study.

Patients characteristics		TILs
	All patients		≤5%		>5%		p-value
	No. 496		No. 323		No. 173
Age at diagnosis, years	No.	%	No.	%	No.	%
Median [min–max]	56.4 [27.3–89.3]		54.8 [30.3–89.3]		57.8 [27.3–84.3]		0.309
Surgery
Conservative surgery	382	77.0	258	79.9	124	71.7	0.039
Mastectomy	114	23.0	65	20.1	49	28.3
Grade
G1–2	273	56.3	215	68.0	58	34.3	<0.001
G3	212	43.7	101	32.0	111	65.7
Missing	11		7		4
Necrosis
Absent	205	44	158	52.0	47	29.0	<0.001
Present	261	56	146	48.0	115	71.0
Missing	30		19		11
Margins
Negative	393	90.8	263	90.4	130	91.6	0.693
Close/positive	40	9.2	28	9.6	12	8.4
Missing	63		32		31
No. excisions
1	445	91.4	289	91.8	156	90.7	0.694
≥2	42	8.6	26	8.3	16	9.3
Missing	9		8		1
Screen detected
No	294	59.5	203	63.0	91	52.9	0.029
Yes	200	40.5	119	37.0	81	47.1
Missing	2		1		1
Radiotherapy†
No	129	40.3	95	43.4	34	33.7	0.100
Yes	191	59.7	124	56.6	67	66.3
Missing	62		39		23

^†Numbers refer to women having a conservative surgery.