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Changes in stroma composition of hypo-perfused pancreatic ductal adenocarcinoma as a result of therapy with gemcitabine (GEM) and MSV-nab-PTX. M2 macrophages (CD204, red) and M1 + M2 macrophages (F4/80, green) were visualized using confocal microscopy. (A) Untreated mice; (B) mice treated 2×; (C) mice treated 12×; (D) M1 macrophages quantification; (E) M1 + M2 macrophages quantification [data from Borsoi et al. (2015)].
