Table 2.
Comparison of breast cancer-specific survival (BCSS) and overall survival (OS) between OBC and non-OBC after subgroup analyses using a multivariate Cox proportional hazard model.
| Nodal status | BCSS | OS | ||
|---|---|---|---|---|
| HR (95% CI) | Pa | HR (95% CI) | Pa | |
| N1 | 0.029 | 0.077 | ||
| OBC | 0.661 (0.456–0.959) | 0.767 (0.572–1.029) | ||
| non-OBC | Reference | Reference | ||
| N2 | 0.030 | 0.039 | ||
| OBC | 0.542 (0.312–0.943) | 0.607 (0.378–0.974) | ||
| non-OBC | Reference | Reference | ||
| N3 | 0.147 | 0.090 | ||
| OBC | 0.735 (0.485–1.114) | 0.716 (0.487–1.053) | ||
| non-OBC | Reference | Reference | ||
| N2/N3 | ||||
| OBC | 0.651 (0.466–0.907) | 0.011 | 0.673 (0.499–0.908) | 0.009 |
| non-OBC | Reference | Reference | ||
| N1/N2/N3 | 0.001 | 0.001 | ||
| OBC | 0.646 (0.504–0.828) | 0.709 (0.575–0.874) | ||
| non-OBC | Reference | Reference | ||
OBC, occult breast cancer; non-OBC, non-occult breast cancer; CI, confidence interval; HR, hazard ratio; BCSS, breast cancer-specific survival; OS, overall survival.
a
P-value was adjusted by a multivariate Cox proportional hazard regression model including age, race, marital status, year of diagnosis, grade, mastectomy, or not, ER status, PR status, HER-2 status, chemotherapy, and radiation. Bold type indicates significance.