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An illustration of the involvement of secreted galectins in host-host glycan and host-microbial glycan interactions. Secreted galectins can exist as free soluble molecules in the extracellular space or associated with cell membrane and extracellular matrix. Secreted galectins may bind host glycans (cell surface glycans), foreign glycans (pathogen surface glycans) and even bridge host glycans and pathogen glycans.
