Table 3.

Comparison of mean OCS scores (percent change) between active and sham treatments one week after treatment.

Statistic	Baseline (Week 1)	Active	Pct Difference (Active − Baseline)	Sham	Pct Difference (Sham − Baseline)	Difference of Pct Differences (Active − Sham)
N	17	17	17	17	17	17
Mean (SD)	6.9 (1.3)	3.5 (2.7)	−51.0 (33.7)	5.8 (2.6)	−15.8 (35.0)	−35.2 (48.2)
Median	7.0	3.3	−60.0	6.7	−4.2	−31.8
Min, Max	4.3, 9.0	0.0, 8.3	−100, 0.0	2.0, 9.0	−72.7, 33.3	−115, 52.4
95% CI	(6.2, 7.6)	(2.1, 4.9)	(−68.3, −33.7)	(4.5, 7.2)	(−33.7, 2.2)	(−60.0, −10.5)
p-value (paired t-test)			<.0001		0.0408	0.0041
p-value (signed-rank test)			<.0001		0.0898	0.0040

All Randomized Patients with Complete Data.

[1] Wilcoxon signed-rank tests were performed to assess percent change from baseline in the OCS score one week after active treatment and sham treatment, separately.

[2] A Wilcoxon signed-rank test was performed to compare the percent change from baseline in the OCS score on active treatment versus sham treatment (Difference of Percent Differences column). A positive value for the difference of percent difference favors sham treatment, while a negative value favors active treatment.

[3] One-sided lower p-values were calculated for all tests.