Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 19;8:753. doi: 10.3389/fcell.2020.00753

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Tumia, Wang, Dong, Ma, Beebe, Chen, Dong, Liu and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effect of eukaryotic initiation factor (eIF)3a expression on the cellular response to ionizing radiation (IR). Western blot analyses (A) and colony formation assay following IR treatment (B) of H1299 cells with transient eIF3a knockdown and NIH3T3 cells with stable eIF3a overexpression compared with their respective control cells. Actin was used as a loading control. Panel (C) shows a summary of eIF3a effects on cellular sensitivity to IR treatments. Relative resistance factor (RRF) was derived by dividing the IC₅₀ of the test cells by that of their control cells (n = 3, **P < 0.01).