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. 2020 Sep 2;20:835. doi: 10.1186/s12885-020-07336-9

Table 2.

Pathway analysis of metabolite changes

Total In Pathway Hits p Value Impact Enriched
Compounds
Citrate cycle (TCA cycle) 20 2 0.00038978 0.125

Citric acid

Isocitric acid

Glyoxylate and dicarboxylate metabolism 50 2 0.0024713 0.0606

Citric acid

Isocitric acid

Linoleic acid metabolism 15 1 0.024711 0.61538 Linoleic acid
beta-Alanine metabolism 28 1 0.045753 0 L-Histidine
Nitrogen metabolism 39 1 0.063291 0.01923 L-Histidine
Histidine metabolism 44 1 0.071183 0.12 L-Histidine
Aminoacyl-tRNA biosynthesis 75 1 0.119 0.01613 L-Histidine