Table 4.
Treatment-related non-hematologic adverse events
| AE* | Any grade AE, N (%) | Grade 3/4 AE, N (%) |
|---|---|---|
| Any AE | 93 (100.0) | 59 (63.4) |
| Infection** | 43 (46.2) | 25 (26.9) |
| Nausea | 41 (44.1) | 0 (0.0) |
| Fatigue | 31 (33.3) | 1 (1.1) |
| Vomiting | 31 (33.3) | 1 (1.1) |
| Hypokalemia | 29 (31.2) | 9 (9.7) |
| Hypoalbuminemia | 25 (26.9) | 0 (0.0) |
| Febrile neutropenia | 23 (24.7) | 23 (24.8) |
| Pneumonia | 21 (22.6) | 13 (14.0) |
| Hypocalcemia | 18 (19.4) | 1 (1.1) |
| Cough | 17 (18.3) | 0 (0.0) |
| Hyponatremia | 16 (17.2) | 2 (2.2) |
| Abdominal pain | 14 (15.1) | 0 (0.0) |
| Pharyngalgia | 14 (15.1) | 1 (1.1) |
| Anorexia | 12 (12.9) | 2 (2.2) |
| Diarrhea | 10 (10.8) | 0 (0.0) |
Abbreviations: AE adverse event
*AEs were assessed based on the CTCAE (NCI Common Terminology Criteria for Adverse Events) version 5.0 and are shown with a frequency ≥ 10%
**Infection included pneumonia