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. 2020 Sep 2;12:77. doi: 10.1186/s13073-020-00773-y

Fig. 11.

Fig. 11

Overview of the involvement of LINC00301 in NSCLC. Schematic representation of our proposed model of FOXC1 upregulates LINC00301 expression, the latter partially mediates oncogenic effects through its epigenetic silencing of EAF2 expression by directly binding with EZH2 to mediate HIF1α activation in the nucleus and by acting as ceRNA for miR-1276 to increase HIF1α expression in the cytoplasm in NSCLC