Skip to main content
. 2020 Sep 2;221:121615. doi: 10.1016/j.talanta.2020.121615

Table.1.

Examples of some biological molecules (glucose, protein, virus and DNA) detection using IO based biosensors.


Bio-sensing method		 IO material A pore size Detected target LOD General advantages Ref.
Enzymatic ZnO and NW 300 nm Glucose 0.01–18 mM Extended linear detection ranges and long-term stability [101]
Enzymatic TiO2 300 nm Glucose 151 μA cm-2 mM-1 Well-defined redox peaks [107]
Colorimetric Hydrogel 220 nm Glucose Not mentioned Novel naked-eye detection of diabetes with multiple reuse [112]
Enzymatic & Photo-electrochemical ZnO 300 nm Glucose 52.4 mA/mM cm2 Improvement the sensor performance [6]
Immunosensor TiO2 275 nm IgG 1 μg/mL Large internal surface area, low fluorescence background [82]
Chemosensors MIP film- SiO2 NPs 500-nm HSA 15- 150 fM Developing the EG-FET transducer [113]
Immunosensor & photoelectrochemical ZnO &
Ag2S NPs		 250 nm AFP 8 pg/mL Matching of energy levels between the conduction bands of Ag2S and ZnO IO [87]
Immunosensor SiO2 IO 263.6 ± 12.9 nm Influenza A H1N1 virus 103 to 105 PFU Sensitively and selectively detection of H1N1 subtype [127]
Immunosensor Hydrogel 350 nm Rotavirus 6.35
μgl/ml		 Having more sensitivity for Rotavirus compare to ELISA [128]
Apta sensor SiO2 370 nm DNA Not mentioned Developing a reliable method for DNA-aptamer immobilization [129]
DNA sensor TiO2-GNPs 200 nm DNA 10 pM Label-free DNA detection of SARS and HIV [130]
DNA sensor Hydrogel- QDs 260 nm DNA 1 nM Developing multiplexing label-free DNA detection [131]
DNA sensor SiO2 and Ag nano sheet 460 nm DNA 5 nM Reporting a facile strategy to preparation SERS-active substrate [132]

NW: nanowire; IOH: invers opal hydrogel, MIP: molecularly imprinted polymer, EG-FET: extended-gate field-effect transistor; PFU: plaque forming unit, AFP: alpha-fetoprotein, GNPs: Gold nanoparticles, QDs: Quantum Dots; SARS: severe acute respiratory syndrome; HIV: human immunodeficiency virus; SERS: Surface enhanced Raman spectroscopy. IOs: Inverse opals, IgG: Immunoglobulin G, HSA: Human serum albumin, ELISA: enzyme-linked immunosorbent assay, H1N1: influenza virus.