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. 2020 Jul 13;10(9):3147–3163. doi: 10.1534/g3.120.401352

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Copyright © 2020 Sendell-Price et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Comparison of observed and simulated F_ST distributions. (A) Frequency distributions of pairwise differentiation (F_ST) for empirical data (chromosome 5 only). (B) Frequency distributions of pairwise differentiation (F_ST) for simulated data. The F_ST values are calculated in 500kb windows. Simulations were conducted using a recombination rate of 3 cM/Mb (the distance between loci for which the expected average number of intervening chromosomal crossovers in a single generation is 0.01). Simulations of divergence with gene flow were conducted under different migration rates (m = 0.01, m = 0.001, and m = 0.0001). Simulation timeframes matched that for each empirical comparison (Early stage - no gene flow: 27 generations; Early stage - gene flow: 47 generations; Mid stage - gene flow: 1,000 generations).