Table 3.
Outcomes.
| Outcome | Systemic anticoagulation |
No systemic anticoagulation |
||||
|---|---|---|---|---|---|---|
| Pre-LDHS patients (n = 13) | Post-LDHS patients (n = 14) | p value | Pre-LDHS patients (n = 28) | Post-LDHS patients (n = 16) | p value | |
| Time to eventa (days), median (IQR) | 4.1 (1.0, 10.1) | 13.9 (9.3, 18.3) | <0.001 | 2.2 (0.7, 6.1) | 4.9 (3.3, 8.5) | 0.03 |
| Bleeding complications, n (%) | 2 (15.4) | 3 (21.4) | 1 | 2 (7.1) | 1 (6.3) | 1 |
| Major | 1 (7.7) | 0 (0) | – | 1 (3.6) | 0 (0) | – |
| CRNMB | 1 (7.7) | 3 (21.4) | – | 0 (0) | 0 (0) | – |
| Minor | 0 | 0 (0) | – | 1 (3.6) | 1 (6.3) | – |
| Death, n (%) | 4 (30.8%) | 2 (14.3%) | 0.38 | 6 (21.4%) | 4 (25.0%) | 1 |
Abbreviations: CRNMB = Clinically Relevant Non-Major Bleeding; IQR = Interquartile range; LDHS = Low dose heparinized saline.
a
“Event” in this situation includes arterial line thrombosis, discontinuation of arterial line when it was no longer needed, or patient death.