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. 2020 Apr 23;1(2):100014. doi: 10.1016/j.patter.2020.100014

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© 2020 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Density Heatmap of Probe Reliability Plotted against Estimates of Genetic and Environmental Effects on DNA Methylation

(A) Additive genetic effects (denoted as “A”), (B) shared environmental effects (denoted as “C”), and (C) non-shared (or unique) environmental effects (denoted as “E”). The variance component is plotted on the x axis and the reliability is plotted on the y axis. Probes with the highest reliability have the highest value of A and lowest value of E. Density is depicted on a spectral scale from low (dark blue) to high (red).