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. 2020 Sep 2;15(9):e0237501. doi: 10.1371/journal.pone.0237501

Table 2. Information concerning treatment of all patients in the retrospective cohort.

Surgical Treatment
Tumor resection n = 6 (35%)
Neck dissection n = 5 (29%)
Radiooncological treatment
Intent of radiotherapy
Definitive radiotherapy [total dose 70–70.4 Gy] n = 12
Adjuvant radiotherapy [total dose 64–64.2 Gy] n = 4
Definitive radiotherapy after neck dissection n = 1
Combined modality treatment
Concomitant chemotherapy n = 14 (82%)
Technique of radiotherapy
Simultaneous integrated boost (by VMAT or TomoTherapy) n = 5
Volumetric Modulated Arc Therapy (VMAT) n = 14
TomoTherapy n = 3
RT parameters
Median single dose 2.0Gy [1.7–2.2Gy]
Median total dose 70.0Gy [64.0–70.4Gy]
Median PTV (50Gy) 1199.7cm3 [591.6–1805.5cm3]
Median duration of RT 49 days [44–53 days]
One patient was re-irradiated because of local recurrence (70.4 Gy as SIB in first course and 50.4Gy in second course, both with concomitant platin-based chemotherapy).