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. 2020 Sep 2;15(9):e0237501. doi: 10.1371/journal.pone.0237501

Table 6. Summary of results of the prospective investigations.

Parameter Proband 1 Proband 2 Proband 3 Proband 4 Proband 5
Swallowing investigation
Morphology post RT / edema inconspicuous post RT / edema inconspicuous post RT /edema
Sensibility reduced reduced reduced reduced normal
FOIS Level 4 6 5 5 3
Aspiration yes yes no no no
Penetration no yes no yes yes
Voice investigation
DSI moderate dysphonia moderate dysphonia light dysphonia slight dysphonia profound dysphonia
Questionnaires
ADI-D rather conspicuous rather inconspicuous rather conspicuous rather conspicuous sure conspicuous
VHI moderate dysphonia no dysphonia no dysphonia no dysphonia no dysphonia
EORTC QLQ-H&N35 Mean (%) 72 38 34 38 41
Further Parameter
Logopedic training before investigation yes no yes no No
Recommendation for logopedic training after investigation yes yes no yes yes
Pulmonary symptoms or disease after RT chron. bronchitis no no no pneumonia
Age at investigation 57 63 57 57 65
TNM at Diagnosis T3 T4+rcT2 T3 T3 T4
Interval RT—investigation [months] 48 6 28 12 16
Total dose RT [Gy] 70 70,4 (+50,4 –reirradiation) 70 66 70
Local recurrence no yes no no no
Neck dissection no no no yes no
Impairment of movement yes no yes yes yes
Feeding tube dependence at investigation no no no no yes