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. 2020 Jul 7;12(15):15436–15445. doi: 10.18632/aging.103610

Figure 4.

Figure 4

Reduction of SPRY1 enhances fibroblast function. (A, B) The level of mRNA SPRY1 in the different groups was measured by qRT-PCR; (C) The levels of cyclin D1 and cyclin D3 mRNA in the different groups were measured by qRT-PCR; (D) CCK-8 assay detected the proliferative ability of fibroblasts in the different groups; (E) The levels of Bcl-2 and Bax mRNA in the different groups were measured by qRT-PCR; (F) The levels of α-SMA, Col 1, and Col 3 mRNA in the different groups were measured by qRT-PCR; (G, H) The concentrations of bFGF and VEGF were measured by ELISA. Data are presented as the mean ± SD from three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001.