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Effects of PB2 on mitochondrial biogenesis and fusion/fission (n = 8). The mRNA of AMPK, Sirt1 and PGC-1α (A), OPA1, Mfn2, Drp1 and Fis1 (B); expressions of AMPK, Sirt1, PGC-1α, OPA1, Mfn2, Drp1 and Fis1, and semi-quantification (C, D). #P ≤ 0.05, ##P ≤ 0.01 compared to control mice; *P ≤ 0.05, **P ≤ 0.01 compared to LPS challenged alone.
