Table 2. Laboratory and radiological findings of non-severe or severe patients of COVID-19 in Guangzhou.
Median (IQR) | P value | Normal range | |||
Total (288) | Non-severe (258) | Severe (30) | |||
Laboratory findings | |||||
WBC (×109/L) | 5.20(4.14-6.44) | 5.14(4.10-6.38) | 5.33(4.42-7.18) | 0.934 | 4-10 |
WBC (×109/L) (No (%)): | .. | .. | .. | <0.0001 | .. |
<4 | 62(21.5) | 57(22.1) | 5(16.7) | .. | .. |
4-10 | 216(75) | 197(76.4) | 19(63.3) | .. | .. |
>10 | 10(3.5) | 4(1.6) | 6(20) | .. | .. |
Lymphocyte count (×109/L) | 1.42(1.04-1.96) | 1.46(1.09-1.97) | 1.03(0.84-1.38) | 0.511 | 1.1-3.2 |
Lymphocyte count (×109/L) (No (%)): | .. | .. | .. | .. | .. |
<1.1 | 91(31.6) | 73(28.3) | 18(60) | <0.0001 | |
Hemoglobin (g/L) | 135.5(123-147) | 136(125-147.3) | 123(114-143.3) | 0.001 | 130-175 |
Platelet count (×109/L) | 194.5(158-247) | 199(160.1-249.3) | 167(140.3-188.5) | 0.043 | 125-350 |
D-dimer (mg/L) | 1110(700-1700) | 1090(680-1600) | 1855(865-3442.5) | 0.052 | <1000 |
D-dimer (mg/L) (No (%)): | .. | .. | .. | 0.106 | .. |
≤1000 | 125(43.9) | 116(45.5) | 9(30) | .. | .. |
>1000 | 160(56.1) | 139(54.5) | 21(70) | .. | .. |
ALT (U/L) | 22.5(14.3-34.5) | 22.1(14.2-33.9) | 25(16.1-49.1) | 0.912 | 9-50 |
ALT (U/L) (No (%)): | .. | .. | .. | 0.039 | .. |
≤50 | 254(88.2) | 231(89.5) | 23(76.7) | .. | .. |
>50 | 34(11.8) | 27(10.5) | 7(23.3) | .. | .. |
AST(U/L) | 18.4(14.9-25.6) | 18.1(14.5-24.5) | 21.9(16.8-41.1) | 0.161 | 15-40 |
AST(U/L) (No (%)): | .. | .. | .. | 0.004 | .. |
≤40 | 256(88.9) | 234(90.7) | 22(73.3) | .. | .. |
>40 | 32(11.1) | 24(9.3) | 8(26.7) | .. | .. |
Myoglobin (μg/L) | 15(8.85-22.4) | 14.4(8.6-21.2) | 27.3(13.1-86.6) | 0.212 | 17.4-105.7 |
Myoglobin (μg/L) (No (%)): | .. | .. | .. | <0.0001 | .. |
≤106 | 269(97.1) | 247(99.2) | 22(78.6) | .. | .. |
>106 | 8(2.9) | 2(0.8) | 6(21.4) | .. | .. |
Creatinine (μmol/L) | 61.8(50.25-76.56) | 62.0(50.4-76.4) | 59.6(45.9-78.1) | 0.428 | 54-106 |
Creatinine (μmol/L) (No (%)): | .. | .. | .. | 0.022 | .. |
≤106 | 279(96.9) | 252(97.7) | 27(90) | .. | .. |
>106 | 9(3.1) | 6(2.3) | 3(10) | .. | .. |
Creatinine kinase (U/L) | 52(36-80) | 52(37-80) | 44.5(27.5-128) | 0.238 | 50-310 |
Creatinine kinase (U/L) (No (%)): | .. | .. | .. | 0.009 | .. |
≤310 | 283(98.6) | 255(99.2) | 28(93.3) | .. | .. |
>310 | 4(1.4) | 2(0.8) | 2(6.7) | .. | .. |
CRP (mg/L) | 9(8-22.72) | 9(8-18.9) | 24(11.7-51.2) | 0.005 | <10 |
CRP (mg/L) (No (%)): | .. | .. | .. | <0.0001 | .. |
≤10 | 175(60.8) | 169(65.5) | 6(20) | .. | .. |
>10 | 113(39.2) | 89(34.5) | 24(80) | .. | .. |
PCT (ng/mL) | 0.13(0.04-32.6) | 0.106(0.035-32.58) | 0.2(0.09-51) | 0.241 | <0.05 |
PCT (ng/mL) (No (%)): | .. | .. | .. | <0.0001 | .. |
<0.05 | 99(35.5) | 96(38.4) | 3(10.3) | .. | .. |
0.05-1.0 | 73(26.2) | 56(22.4) | 17(58.6) | .. | .. |
1..0-10 | 6(2.2) | 6(2.4) | 0(0) | .. | .. |
>10 | 101(36.2) | 92(36.8) | 9(31) | .. | .. |
BNP (ng/L) | 35(13-117.5) | 18.5(9.75-40.25) | 213(45-399) | 0.014 | <100 |
TNI (μg/L) | 0.004(0.001-0.009) | 0.003(0.001-0.007) | 0.027(0.010-0.099) | 0.033 | <0.03 |
TNI (μg/L) (No (%)): | .. | .. | .. | <0.0001 | .. |
≤0.03 | 168(88.4) | 159(92.4) | 9(50) | .. | .. |
>0.03 | 22(11.6) | 13(7.6) | 9(50) | .. | .. |
Chest radiography findings | |||||
Unilateral pneumonia | 31(10.8) | 31(12.1) | 0(0) | 0.044 | .. |
Bilateral pneumonia | 241(83.7) | 212(82.2) | 29(96.7) | 0.042 | .. |
WBC, White blood cell; ALT, Alanine transaminase; AST, Aspartate aminotransferase; CRP, C-reactive protein; PCT, Procalcitonin; BNP, Brain natriuretic peptide; TNI, Troponin I.
*P values indicate differences between Severe and Non-severe patients. P<0.05 was considered statistically significant.