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. 2020 Jul 19;12(15):15392–15413. doi: 10.18632/aging.103601

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Copyright © 2020 Hao et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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overall survival in glioma patients with low and high PDIA3 expression. Kaplan – Meier analysis of overall survival was performed in pan-glioma (A, D), LGG (B, E) and GBM (C, F) patients based on TCGA and CGGA datasets. (G) Subgroup analyses estimating prognostic value of PDIA3 in OS in different cancer types from TCGA. The length of horizontal line represents the 95% confidence interval for each group. The vertical dotted line represents the HR of all patients. HR < 1.0 indicates that high TMEscore is a favorable prognostic biomarker. Number of patients is indicated. (H). Subgroup analyses estimating prognostic value of PDIA3 in DSS in different cancer types from TCGA. The length of horizontal line represents the 95% confidence interval for each group. The vertical dotted line represents the HR of all patients. HR < 1.0 indicates that high TMEscore is a favorable prognostic biomarker. Number of patients is indicated. KICH, Kidney Chromophobe; UVM, Uveal Melanoma; LGG, Brain Lower Grade Glioma; ACC, Adrenocortical carcinoma; THCA, Thyroid carcinoma; THYM, Thymoma; KIRP, Kidney renal papillary cell carcinoma; CESC, Cervical squamous cell carcinoma and endocervical adenocarcinoma; GBM, Glioblastoma multiforme; PAAD, Pancreatic adenocarcinoma; KIRC, Kidney renal clear cell carcinoma; MESO, Mesothelioma; STAD, Stomach adenocarcinoma; OV, Ovarian serous cystadenocarcinoma; LUAD, Lung adenocarcinoma; BLCA, Bladder Urothelial Carcinoma; HNSC, Head and Neck squamous cell carcinoma; SARC, Sarcoma; LIHC, Liver hepatocellular carcinoma; UCEC, Uterine Corpus Endometrial Carcinoma; SKCM, Skin Cutaneous Melanoma; COAD, Colon adenocarcinoma; ESCA, Esophageal carcinoma; UCS, Uterine Carcinosarcoma; LUSC, Lung squamous cell carcinoma; BRCA, Breast invasive carcinoma; CHOL, Cholangiocarcinoma; READ, Rectum adenocarcinoma; PRAD, Prostate adenocarcinoma; LAML, Acute Myeloid Leukemia; PCPG, Pheochromocytoma and Paraganglioma; TGCT, Testicular Germ Cell Tumors; DLBC, Lymphoid Neoplasm Diffuse Large B-cell Lymphoma. P-values were obtained from the log-rank test.