Table 2.
Lesion characteristics
| Variable | All | De novo | BMS-ISR | DES-ISR | p value |
|---|---|---|---|---|---|
| Number of lesions | 496 (100%) | 386 (77.8%) | 19 (3.8%) | 91 (18.4%) | – |
| Target vessel | |||||
| LAD | 255 (51.4%) | 192 (49.7%) | 14 (70.0%) | 49 (53.8%) | 0.492 |
| CX | 111 (22.4%) | 89 (23.1%) | 2 (10.5%) | 20 (22.0%) | |
| RCA | 116 (23.4%) | 95 (24.6%) | 3 (15.8%) | 18 (20.0%) | |
| Graft | 6 (1.2%) | 3 (0.8%) | 0 (0.0%) | 3 (3.3%) | |
| Ramus intermedius | 7 (1.4%) | 6 (1.6%) | 0 (0.0%) | 1 (1.1%) | |
| Unknown | 1 (0.2%) | 1 (0.3%) | 0 (0.0%) | 0 (0.0%) | |
| Total occlusion | 25 (5.0%) | 19 (4.9%) | 4 (21.1%) | 2 (2.2%) | 0.003 |
| Chronic total occlusion | 15 (3.0%) | 13 (3.4%) | 1 (5.3%) | 1 (1.1%) | 0.443 |
| Thrombus burden | 7 (1.4%) | 5 (1.3%) | 1 (5.3%) | 1 (1.1%) | 0.345 |
| Diffuse vessel disease | 181 (36.5%) | 157 (40.7%) | 5 (26.3%) | 19 (20.9%) | 0.001 |
| Calcification | 168 (33.9%) | 128 (33.2%) | 10 (52.6%) | 30 (33.0%) | 0.212 |
| Ostial lesion | 67 (13.5%) | 52 (13.5%) | 1 (5.3%) | 14 (15.4%) | 0.502 |
| Bifurcation lesion | 105 (21.2%) | 101 (26.2%) | 1 (5.3%) | 3 (3.3%) | < 0.001 |
| Severe tortuosity | 28 (5.6%) | 26 (6.7%) | 0 (0.0%) | 2 (2.2%) | 0.133 |
| AHA/ACC type B2/C lesion | 180 (36.3%) | 130 (33.7%) | 13 (66.8%) | 37 (40.7%) | 0.006 |
| Number of diseased vessels | |||||
| Single | 171 (35.6%) | 120 (31.1%) | 4 (21.1%) | 52 (57.1%) | < 0.001 |
| Double | 216 (44.9%) | 193 (50.0%) | 7 (36.8%) | 22 (24.2%) | |
| Triple | 94 (19.5%) | 73 (18.9%) | 9 (42.1%) | 17 (18.7%) | |
| Reference diameter (mm)a | 2.74 ± 0.44 | 2.63 ± 0.37 | 3.05 ± 0.29 | 3.15 ± 0.42 | < 0.001 |
| Lesion lengtha | 16.8 ± 10.2 | 16.7 ± 10.4 | 20.1 ± 8.9 | 16.2 ± 9.8 | 0.320 |
| Degree of stenosis (%)a | 84.9 ± 10.0 | 85.1 ± 9.9 | 83.2 ± 9.9 | 84.5 ± 9.9 | 0.630 |
| TIMI flow prior to intervention | |||||
| 0 | 25 (5.0%) | 18 (4.7%) | 4 21.1%) | 3 (3.3%) | 0.005 |
| 1 | 16 (3.2%) | 15 (3.9%) | 0 (0.0%) | 1 (1.1%) | |
| 2 | 168 (33.9%) | 140 (36.3%) | 3 (15.8%) | 25 (27.5%) | |
| 3 | 287 (57.9%) | 213 (55.2%) | 12 (63.1%) | 62 (68.1%) | |
AHA/ACC American College of Cardiology/American Heart Association, BMS-ISR in-stent restenotic lesions in bare metal stents, CX left circumflex artery, DES-ISR in-stent restenotic lesions in drug-eluting stents, LAD left anterior descending, RCA right coronary artery, TIMI thrombolysis in myocardial infarction
aSingle-factor ANOVA, otherwise χ2 or Fisher’s Exact Test whenever applicable