Why carry out this study?

Approximately 6.1% of women in the USA (2012) have endometriosis, which is associated with potentially painful symptoms, significant healthcare costs, work absenteeism, and decreased productivity.

This retrospective claims database analysis evaluated the long-term indirect costs and risks of work loss incurred by women with endometriosis compared with matched controls without endometriosis.

What was learned from the study?

Compared with controls, women with endometriosis were significantly more likely to experience any work loss event, including a leave of absence and short-term disability, as well as lower salary and salary growth in the 5 years after diagnosis.

This study provides real-world evidence that endometriosis is associated with a considerable indirect burden, confirmed across multiple outcomes and robust in sensitivity analyses.