Table 2.
Treatment patterns
| Pooled population n = 214 |
||
|---|---|---|
| n/Mean | %/SD | |
| Persistence | 179 | 83.6% |
| Discontinuation | 35 | 16.4% |
| Time to discontinuation, days (among discontinued patients) | 137.7 | 76.1 |
| Re-start of index biological | 9 | 25.7% |
| Time to restart of UST, days | 206.0 | 79.0 |
| Switched from UST | 3 | 8.6% |
| Time to switch, days | 172.7 | 63.0 |
| Discontinued without restart or switch | 23 | 65.7% |
| Time to discontinuation without restart or switch, days | 152.2 | 73.5 |
| Duration of therapy among all patients | 328.7 | 89.9 |
| Medication adherence | ||
| Medication possession ratio (MPR) | 0.79 | 0.30 |
| MPR ≥ 80% | 112 | 52.3% |
| Proportion of days covered (PDC) | 0.73 | 0.25 |
| PDC ≥ 80% | 103 | 48.1% |
CD Crohn’s disease; SD standard deviation; UST ustekinumab