Table 2.
Bias, precision, accuracy (95% CIs) of CKD-EPI, FAS and LMR in the CKD and community cohorts
| Equations | Bias | Precision | Absolute error (%) | P10 (%) | P30 (%) |
|---|---|---|---|---|---|
| (mL/min/1.73 m2) | (mL/min/1.73 m2) | ||||
| CKD cohorts (n = 8365) | |||||
| CKD-EPI | 3.8 (3.5–4.1) | 16.6 (16.1–17.0) | 16.0 (15.6–16.4) | 33.4 (32.3–34.4) | 76.6 (75.7–77.5) |
| FAS | 3.3 (3.0–3.6) | 15.5 (15.0–16.0) | 15.3 (14.9–15.7) | 34.3 (33.3–35.3) | 76.5 (75.6–77.4) |
| LMR | −1.4 (−1.7, −1.1) | 14.4 (14.0–14.8) | 14.1 (13.8–14.5) | 35.9 (34.9–37.0) | 83.5 (82.7–84.3) |
| Community cohorts (n = 6759) | |||||
| CKD-EPI | 2.1 (1.8–2.6) | 17.2 (16.7–17.7) | 10.4 (10.1–10.7) | 48.6 (47.4–49.8) | 91.0 (90.4–91.7) |
| FAS | −1.4 (−1.8, −1.0) | 17.8 (17.3–18.3) | 10.8 (10.5–11.0) | 46.9 (45.7–48.0) | 91.9 (91.3–92.6) |
| LMR | −6.7 (−7.0, −6.4) | 16.7 (16.2–17.1) | 11.5 (11.2–11.8) | 43.7 (42.5–44.9) | 92.8 (92.1–93.4) |
Median bias (eGFR − mGFR) and precision (IQR) expressed in mL/min/1.73 m2, absolute error expressed as median absolute percentage error |eGFR − mGFR|/mGFR and P10 and P30 accuracy (percentage of GFR estimates within 10% and 30% of mGFR).