Table 3.
Diagnostic correctness (bias stratified by mGFR) in the two cohort types combined (CKD and community; n = 15 124)
| Age intervals (years) |
||||
|---|---|---|---|---|
| mGFR | 18–39 | 40–59 | 60–69 | ≥70 |
| <30, number | 101 | 270 | 338 | 1073 |
| CKD-EPI | 5.0 (3.6–7.0) | 1.4 (0.7–2.8) | 2.9 (2.1–3.9) | 2.0 (1.5–2.5) |
| FAS | 9.7 (7.8–12.7) | 6.6 (5.5–7.6) | 5.6 (4.8–6.4) | 2.9 (2.5–3.3) |
| LMR | 2.8 (1.6–3.8) | 1.2 (0.4–1.9) | 1.8 (1.1–2.5) | 0.2 (−0.2, 0.7) |
| 30–59, number | 381 | 656 | 767 | 1443 |
| CKD-EPI | 13.4 (11.5–15.5) | 3.7 (2.6–5.0) | 3.4 (2.0–4.4) | 4.0 (3.4–4.6) |
| FAS | 14.5 (13.0–16.4) | 7.1 (6.0–8.3) | 2.7 (1.8–3.8) | −0.2 (−0.8, 0.2) |
| LMR | 6.3 (4.1–8.6) | 1.3 (0.3–2.6) | 0.6 (−0.9, 1.9) | −0.3 (−0.8, 0.5) |
| 60–89, number | 736 | 1772 | 1556 | 1133 |
| CKD-EPI | 15.6 (13.6–17.3) | 8.0 (7.3–8.9) | 7.0 (6.2–7.6) | 5.9 (5.1–5.6) |
| FAS | 10.9 (9.5–12.2) | 4.4 (3.8–5.1) | −0.4 (−1.0, 0.3) | −4.5 (−5.5, −3.8) |
| LMR | 2.6 (1.4–3.8) | −0.1 (−0.7, 0.5) | −2.2 (−2.7, −1.6) | −4.4 (−5.2, −3.9) |
| 90–119, number | 1278 | 2088 | 798a | 147a |
| CKD-EPI | 10.4 (9.2–11.5) | −1.9 (−2.5, −1.4) | −5.3 (−6.1, −4.5) | −9.5 (−12.2, −7.0) |
| FAS | 4.4 (3.4–6.0) | −2.8 (−3.4, −2.2) | −9.5 (−10.8, −8.5) | −14.2 (−16.8, −12.7) |
| LMR | −9.0 (−9.8, −8.3) | −12.0 (−12.5, −11.5) | −15.1 (−16.0, −14.1) | −20.0 (−22.3, −18.1) |
| ≥120, number | 338 | 249 | –a | –a |
| CKD-EPI | −5.2 (−7.3, −2.8) | −23.9 (−26.4, −21.2) | ||
| FAS | −5.8 (−9.3, −3.3) | −17.9 (−21.4, −15.1) | ||
| LMR | −25.7 (−27.0, −24.2) | −32.4 (−35.7, −31.0) | ||
Median bias (eGFR – mGFR in mL/min/1.73 m2; 95% CIs) of CKD-EPI, FAS and LMR stratified by mGFR and age (years). The lowest bias is marked with bold and italic in each stratum.
a
mGFR intervals ≥120 were collapsed with 90–119 due to small numbers (n < 100).