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. 2020 Sep 2;6(36):eaba3992. doi: 10.1126/sciadv.aba3992

Fig. 7. Centrosome dynamics defects after PKA delocalization.

Fig. 7

(A) Maximal distance between nucleus and centrosome during CK of neurons electroporated with centrin-RFP and GFP or dnPKA-GFP in Kif3alox/lox background: The maximal distance was decreased in dnPKA neurons [GFP 12.32 ± 0.42 μm versus dnPKA 10.46 ± 0.38 μm; one-way Kruskal-Wallis test (χ2 = 13.54, P = 0.003, df = 3), followed by Nemenyi test (**P < 0.01)]. The black line represents the median. (B) Percentage of CK efficiency in neurons electroporated with centrin-RFP and GFP or dnPKA-GFP in Kif3alox/lox background: The percentage of inefficient CK was increased in dnPKA neurons (GFP 26% versus dnPKA 37%, Pearson’s χ2 test = 6.06, P = 0.027). GFP: N = 3, n = 50; dnPKA: N = 3, n = 86.