FIGURE 4.
True-positive case of nodal recurrence in a 77-year-old man with history of prostate carcinoma, Gleason 4 + 4, T3aN0, originally treated with RP who presented with BCR, PSA from 0.16 to 0.59 ng/mL in a 6-month period. Initial axial CT (A), PET/CT fusion (B), and PET (C) images show a 5-mm left internal iliac lymph node (arrows) that exhibits 18F-fluciclovine activity above blood pool, SUVmax of 2.2 compared with blood pool SUVmean of 1.3. Follow-up scan (D–F) performed 6 months later shows interval increase in size, now 8 mm, and activity, now SUVmax of 6.7. PSA also increased to 3.02 ng/mL.