Skip to main content
. 2020 Jan 13;14(2):1482–1491. doi: 10.1021/acsnano.9b06047

Figure 1.

Figure 1

Scheme for the miRNA-stimulated constitutional dynamic networks (CDNs)-guided release of loads from DNA-based microcapsules. (A) The T1 (miRNA-155)-triggered reconfiguration of CDN “S” to CDN “X” leads to the guided unlocking of the DOX-D-loaded microcapsules (MC-1). The T2 (miRNA-124)-triggered reconfiguration of CDN “S” to CDN “Y” leads to the guided unlocking of the CPT-CMC-loaded microcapsules (MC-2). (B) Unlocking principle of p-bridged DOX-D-loaded MC-1 and the q-bridged CPT-CMC-loaded MC-2 through the hybridization of the p/p′ and q/q′. The sequences shown in the scheme are listed from 5′ to 3′.