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Agarose gel electrophoresis (2%) analysis of the construction of the tetrahedron sensing modules described in Scheme 1. Lane 1, strand 1; lane 2, duplex strand 1 + 2; lane 3, Y-shaped structure consisting of strands 1 + 2 + 3; lane 4, intergrated tetrahedra module composed of 1 + 2 + 3 + 4; lane 5, intergrated tetrahedra modified with miRNA-21; lane 6, intergrated tetrahedra carrying miRNA-155; lane 7, intergrated tetrahedra carrying miRNA-221.
