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. 2020 Jul 11;150(9):2314–2321. doi: 10.1093/jn/nxaa183

FIGURE 2.

FIGURE 2

The figure shows changes in glucose and insulin during an OGTT in the entire cohort (A and B) and changes in 2-h glucose and HFF% in the four subjects with IGT (C and D). (A) Plasma glucose and (B) plasma insulin concentrations during an oral-glucose-tolerance test before (week 0) and after (week 12) a 12-wk low n–6:n–3 PUFA ratio dietary intervention. Data are observed mean ± SEM, n = 17. Individual changes in (C) 2-h plasma glucose and (D) HFF% before (week 0) and after (week 12) a 12-wk low n–6:n–3 PUFA ratio dietary intervention for the 4 subjects that presented with IGT at week 0. Of the 4 subjects with IGT at week 0, 3 subjects showed reduced 2-h glucose and HFF% values by week 12 of the diet intervention. The open circle indicates the only subject that progressed to T2D and increased HFF% by week 12 of the intervention. Total AUCs for week 0 and week 12 for (A) plasma glucose and (B) plasma insulin compared with Wilcoxon's signed rank test. HFF%, hepatic fat fraction; IGT, impaired glucose tolerance; T2D, type 2 diabetes.