Fig. 5.

LSPR response in detecting antibodies against the SARS-CoV-2 spike protein in the opto-microfluidic platform. (a) Typical sensorgram corresponding to the detection of 1ng/mL of anti-SARS-CoV-2 spike protein antibody in PBS. The vertical dashed lines highlight the initial wavelength stabilization in PBS, the injection of the antibody sample, and the final washing step with PBS to remove weakly bonded molecules. (b) LSPR responses at different anti-SARS-CoV-2 spike protein antibody concentrations. Each data point corresponds to the average data from triplicate experiments, with the error bars denoting the standard deviation.