Fig. 5.

Wound healing assay for different Wnt signaling manipulators in A2780 and A2780cis: a Cell migration in A2780 and A2780cis was significantly reduced through the addition of 100 µM SB216763 or 50 nM triptolide after 48 and 72 h compared to controls. Treatment with XAV939 did not affect migration ability at all (n = 3 per column, mean, *p < 0.05/ **p < 0.01/ ***p < 0.001 by Sidak's multiple comparisons test, wound area after 0 h was set 100%). b Representative images of the wound area in A2780 and A2780cis 72 h after treatment with 100 µM SB216763 compared to controls with 2‰ DMSO. While controls showed a confluent monolayer of cells, in SB216763 treated cells a remaining wound area is visible