Table 2.
Retrospective analysis of rates of development from morulae to blastocysts
| Sage | CSC | |||
|---|---|---|---|---|
| < 37 years | > 37 years | < 37 years | > 37 years | |
| Number of patients | ||||
| 35* | 29* | 16* | 29* | |
| Number of cultured | ||||
| 251 | 207 | 145 | 186 | |
| Number of morulae | ||||
| 174 | 117 | 106 | 134 | |
| Rate (%)† | 69.3a | 56.5a | 73.1 | 72.0 |
| Number of blastocysts on day 5 | ||||
| 135 | 75 | 92 | 86 | |
| Rate (%)‡ | 77.6a | 64.1a | 86.8b | 64.2b |
| Number of morphologically good blastocysts on day 5 | ||||
| 54 | 24 | 32 | 31 | |
| Rate (%)‡ | 31 | 20.5 | 30.2 | 23.1 |
| Number of blastocysts on day 6 | ||||
| 160 | 100 | 97 | 111 | |
| Rate (%)‡ | 92.2a | 85.5a | 91.5b | 82.8b |
| Number of morphologically good blastocysts on day 6 | ||||
| 65 | 35 | 42 | 34 | |
| Rate (%)‡ | 37.4 | 29.9 | 39.6b | 25.4b |
Embryos were cultured in SAGE 1-Step™ medium (Sage) or Continuous Single Culture® medium (CSC) as described in the Methods. *Embryos obtained from 3 patients were randomly divided and cultured in two media. †The rate of morulae per cultured fertilized ova, ‡The rate of blastocysts per morulae. abValues with same superscripts within each column differ (P < 0.05)