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. 2020 Jun 23;37(8):1963–1974. doi: 10.1007/s10815-020-01867-7

Table 4.

Placental histopathology characteristics

Characteristic Myoma group Non-myoma group p value
Placental weight (g) 484.9 ± 123.8 478.5 ± 112.7 0.62
Small (< 10 percentile) placental weight (n (%)) 23 (22.8) 232 (22.8) 0.99
Large (> 90 percentile) placental weight (n (%)) 11 (10.9) 89 (8.7) 0.49
Placental thickness (cm) 1.4 (1.3–1.5) 2.0 (1.5–2.4) 0.001
Cord length (cm) 50 (41–57) 50 (42–60) 0.31
Assisted placental delivery (n (%)): 6 (5.9) 19 (1.9) 0.01
Placenta previa (n (%)) 1 (1.0) 3 (0.3) 0.26
Placenta accreta (n (%)) 1 (1.0) 1 (0.1) 0.04
Anatomic disorders (n (%)):

  - Single umbilical artery

  - Marginal insertion

  - Furcate cord insertion

  - Velamentous insertion

  - Circummarginate membranes insertion

  - Circumvallate membranes insertion

  - True knot

  - Hypercoiled umbilical cord

  - Bilobed placenta

  - Accessory lobe

0 (0)

17 (16.8)

2 (2.0)

8 (7.9)

9 (8.9)

4 (4.0)

0 (0)

3 (3.0)

0 (0)

2 (2.0)

10 (1.0)

244 (23.9)

3 (0.3)

94 (9.2)

138 (13.6)

7 (0.7)

10 (1.0)

5 (0.5)

18 (1.8)

13 (1.3)

0.32

0.11

0.01

0.66

0.19

0.001

0.32

0.005

0.18

0.56

Inflammatory disorders (n (%)):

  - Acute chorioamnionitis with moderate to severe maternal inflammatory response

  - Acute chorioamnionitis with moderate to severe fetal inflammatory response

  - Chronic deciduitis

  - Villitis of unknown etiology

5 (5.0)

2 (2.0)

3 (3.0)

4 (4.0)

66 (6.5)

26 (2.6)

5 (0.5)

36 (3.5)

0.55

0.72

0.005

0.83

Maturation disorders (n (%)):

  - Accelerated villous maturation

  - Delayed villous maturation

  - Distal villous hypoplasia

  - Increased syncytial knotting

12 (11.9)

1 (1.0)

3 (3.0)

7 (6.9)

65 (6.4)

23 (2.3)

15 (1.5)

72 (7.1)

0.03

0.39

0.25

0.96

Vascular disorders (n (%)):

  - Retroplacental hematoma/hemorrhage

  - Cord thrombosis

  - Intervillous thrombosis

  - Intervillous non-subchorionic fibrin

  - Focal Intramural fibrin

  - Villous infarction

  - Villous agglutination

  - Avascular villi

  - Perivillous fibrin deposition

  - Maternal vasculopathy

  - Fetal vasculopathy

  - Chorionic thrombosis

  - Chorangiosis

  - Subchorionic fibrin

  - Subchorionic thrombi

  - Fetal vascular malperfusion (one criteria)

  - Fetal vascular malperfusion (> one criteria)

  - Maternal vascular malperfusion (one criteria)

  - Maternal vascular malperfusion (> one criteria)

2 (2.0)

0 (0)

8 (7.9)

0 (0)

2 (2.0)

3 (3.0)

0 (0)

1 (1.0)

13 (12.9)

11 (10.9)

0 (0)

1 (1.0)

10 (9.9)

4 (4.0)

11 (10.9)

4 (4.0)

1 (1.0)

39 (38.6)

15 (14.9)

52 (5.1)

2 (0.2)

57 (5.6)

3 (0.3)

1 (0.1)

32 (3.1)

9 (0.9)

18 (1.8)

100 (9.8)

49 (4.8)

3 (0.3)

9 (0.9)

103 (10.1)

23 (2.3)

42 (4.1)

40 (3.9)

15 (1.5)

409 (40.2)

127 (12.5)

0.39

0.66

0.34

0.59

0.0001

0.92

0.34

0.56

0.33

0.009

0.58

0.91

0.95

0.29

0.002

0.98

0.69

0.76

0.49

Nucleated red blood cells (n (%)) 1 (1.0) 11 (1.1) 0.93
Chorangioma (n (%)) 3 (3.0) 5 (0.5) 0.005

Data are median (quartiles) or mean ± standard deviation unless stated otherwise