Table 2.

Clinical characteristics of the patients with TUBB8 variants

Family	Age (years)	Duration of infertility (years)	Previous IVF and ICSI cycles	Total oocytes retrieved	GV oocytes	MI oocytes	Immature oocytes of unknown stage	PB1 oocytes	Oocytes with abnormal morphology	Fertilized oocytes	No. of embryos that could be cleaved	Usable embryos	Outcome of embryo transfer
1	30	6	1	11	0	11	0	0	0	0	0	0	/
2	32	3	1	7	0	4	0	2	1	2	0	0	/
3	38	8	3	44	0	0	44	0	0	9	0	1	Failure
4	33	6	2	26	0	0	26	0	0	15	3	0	/
5	29	7	3	40	0	0	40	0	0	26	12	4	Failure
6	36	12	3	39	0	0	39	0	0	0	0	0	/
7	27	6	2	29	3	13	0	13	0	7	1	0	/
8	30	7	3	51	0	0	51	0	0	24	16	3	/
9	30	4	2	13	0	9	0	2	2	0	0	0	/
10	26	/	1	10	0	9	0	1	0	1	0	0	/
11	35	9	4	31	0	0	20	11	0	11	8	2	Failure
12	31	7	3	51	0	1	50	0	44	44	0	0	/
13	31	4	2	17	0	0	5	12	0	2	1	1	Failure
14	34	6	2	21	0	2	2	0	17	2	0	0	/
15	23	3	1	11	0	0	0	4	7	4	0	0	/
16	40	13	3	21	0	8	0	8	5	7	6	4	Failure
17	30	6	1	9	0	4	0	0	5	4	4	0	/
19	37	15	2	59	14	45	0	0	0	0	0	0	/
20	33	/	2	37	2	5	0	28	2	19	19	3	/
21	29	5	1	5	0	4	0	0	0	1	0	0	/
22	32	/	1	17	0	0	0	0	17	0	0	0	/
23	31	4	3	22	0	0	22	0	0	4	0	0	/
25	29	6	1	6	0	0	0	6	0	6	2	0	/
26	32	4	2	25	4	13	0	8	0	4	1	0	/
27	/	9	3	29	0	0	0	29	0	26	12	1	Failure
28	27	4	1	15	0	0	15	0	0	8	4	0	/
29	29	3	1	12	5	5	0	2	0	2	2	2	Failure
30	28	5	2	20	20	0	0	0	0	0	0	0	/
31	26	7	2	24	0	24	0	0	0	0	0	0	/
32	31	/	3	49	0	0	49	0	0	24	14	2	Failure
33	34	8	2	4	0	0	0	2	2	2	2	0	/
34	32	6	2	24	0	0	24	0	0	12	8	0	/
35	37	9	2	18	0	0	0	18	0	11	11	0	/
36	25	2	1	20	0	0	20	0	0	17	14	0	/
37	30	/	2	39	0	39	0	0	0	0	0	0	/
38	30	5	2	13	2	9	0	2	0	1	1	0	/
39	33	11	1	12	0	2	0	8	2	3	1	0	/

Families 18 and 24 had no clinical information

IVF, in vitro fertilization; ICSI, intracytoplasmic sperm injection; GV, germinal vesicle; MI, metaphase I; PB1, first polar body; /, not available