Table 3.
Predictors of recurrent venous thromboembolism.
| Variable | OR per | Univariate | Multivariate* | ||
|---|---|---|---|---|---|
| OR (95% CI) | p-value | OR (95% CI) | p-value | ||
| BMI | 1 kg/m2 | 1.15 (1.04–1.27) | 0.005 | 1.05 (0.93–1.19) | 0.40 |
| PTS | No/yes | 10.25 (4.80–22.75) | < 0.001 | – | – |
| Smoking | No/yes | 0.48 (0.22–0.98) | 0.043 | – | – |
| Trauma | No/yes | 0.22 (0.05–0.64) | 0.004 | – | – |
| Proximal DVT | No/yes | 3.51 (1.40–10.71) | 0.006 | – | – |
| Fibrinogen | 1 g/L | 1.38 (0.97–1.96) | 0.072 | 0.92 (0.59–1.43) | 0.72 |
| HRG | 1 µg/mL | 1.07 (1.04–1.27) | 0.004 | – | – |
| CRP | 1 mg/L | 1.39 (1.16–1.72) | < 0.001 | 1.27 (1.00–1.61) | 0.047 |
| TAFI activity | 1 µg/mL | 1.14 (1.08–1.21) | < 0.001 | 1.08 (1.01–1.15) | 0.023 |
| Plasma clot permeability | 1 × 10−9cm2 | 0.36 (0.24–0.52) | < 0.001 | 0.43 (0.27–0.66) | < 0.001 |
| Maximum absorbance (405 nm) | 0.01 | 1.16 (1.10–1.24) | < 0.001 | – | – |
| Clot lysis time | 1 min | 1.04 (1.02–1.07) | < 0.001 | 1.01 (0.98–1.04) | 0.47 |
For abbreviations, please see Table 1. Multivariate model where variable selection was performed using least absolute shrinkage and selection operator (LASSO) algorithm and adjusted for body mass index (BMI) and fibrinogen.